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Description
(2) glutathione depletion disrupts redox balance

Tryptophan serves as a critical amino acid in this context, being primarily metabolized through the kynurenine pathway during inflammatory responses due to the activity of indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) 51,52

Some examples are steroids, erythropoietin (EPO), and human growth hormone (hGH)

Summary Inappropriate management of postoperative pain in children can result in changes that could have a lasting negative impact

doi: 10.1016/j.yexcr.2015.10.004
