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Therapeutic trial with riboflavin and/or Coenzyme Q10 resulted in decreased C4- and C5-acylcarnitines in one patient and mild improvements in chronic mucoid diarrhea and motor and cognitive functions in three patients [152]

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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, a class of drugs that regulate appetite, slow digestion, and help control blood sugar

These molecules were specifically found to be direct inhibitors of the Sec4-class small GTPase Sav1, which impairs the late post-Golgi secretory pathway and reveals a novel method of compromising cell wall integrity and preventing fungal cell growth (Beattie et al., 2020)

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