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It is hypothesized that apathy is the result of communication failure between the anterior cingulum and other brain structures due to the AD-induced neurological damage (Kim et al., 2011)

10.1016/j.jacbts.2018.04.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 44.Huang H, Taraboletti A, Shriver LP

C., Maxwell D

Elevated levels of homocysteine (Hcy) and its metabolites, such as Hcy-thiolactone and N-Hcy-protein, are strongly associated with endothelial dysfunction and cardiovascular diseases (CVD) [107]
