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However, the complex etiology of DED necessitates a more comprehensive therapeutic approach that can interfere with the intracellular signaling pathways, which are responsible for the development of pathological changes in the eyes of DED patients [6,7]

Mahmoudian, and F

Clin Trials J 1990;27:155-163

dietary supplementation may be medically recommended

Understanding how TMAO affects various immune cells, including macrophages, DCs, T lymphocytes, B lymphocytes, and natural killer (NK) cells, is of great significance in further unraveling the complex mechanisms of immunometabolism and potentially developing new therapeutic strategies
