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when cells are exposed to this stimulus, the NRF2Keap1 complex is disrupted, allowing NRF2 to escape and resulting in Keap1-mediated degradation

[DOI] [PubMed] [Google Scholar] 3.Xu Y., Jiang W., Chen G

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In conclusion, this meta-analysis confirmed that L-carnitine supplements can increase LVEF, stroke volume, cardiac output, decrease left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), and left ventricular end-systolic volume (LVESV), serum levels of BNP and NT-proBNP, as well as a satisfactory safety

The administration of LC inhibits the impairment of Leydig and Sertoli cells caused by oxidative stress 93 , which in turn resulted in increased hormonal levels of testosterone, FSH, and LH 94