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The level of oxidative stress in diabetes increases due to the ongoing disease process and the imbalance between oxidation and antioxidant defense

However, this significance was not observed in the meta-analysis of the two randomized controlled trials (RCTs) conducted exclusively in vivo

While we are still a long way away from pinpointing an analogous pathogenic species in MS, once identified, a specific immunotherapy targeting the relevant misfolded proteins, rather than downstream immune effectors as is the current approach, could be more effective in the progressive stages of MS

Lyle Peterson , Dr

Aging Cell 18 , e13004 (2019)