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In the United States, you need to check the first in human trials FDA regulations

Basic fibroblast growth factor promotes bone ingrowth in porous hydroxyapatite

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No findings suggest clinical relevance, therapeutic intent, physiological application, or suitability for human or veterinary use

It is thought to produce an analgesic effect by reducing levels of pain mediators such as tumor necrosis factor-alpha, prostaglandins, interleukin 1-beta, and beta-endorphins, as well as by increasing local microcirculation