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In addition, pathways including the IGF, CSF, and VCAM pathways were distinct in the PT group, suggesting newly established communication patterns between the cell types

With the increasing use of multi-omics technologies, the field is moving toward a more integrated understanding marked by a shift from phenotype-based description to mechanism-oriented interpretation

doi: 10.3389/fnins.2021.767405

However, commercially available cyclases are limited in their ability to cyclize peptides smaller than 10 amino acids

However, clinical translation faces challenges, including pathway redundancy, off-target effects, and the need for precise dosing to balance protective and detrimental outcomes