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Due to predicaments about how to select the most appropriate grafting to immobilized aptamer on the solid-phase carrier, loading of biotinylated oligonucleotides on streptavidin-coated SMBs was investigated previously in our lab 35

Calcium overload is not only capable of the induction of proteases and lipases, but it also facilitates mitochondrial permeability transition, eventually causing the release of pro-apoptotic factors from the mitochondria to the cytoplasm (52,163)

Intracellular iron that exceeds the cells storage capacity leads to the Fenton reaction-induced generation of ROS that can promote cancer-causing mutations, leading to cancer progression or, if ROS levels are high enough, cytotoxicity