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Depression symptoms can differ significantly between patients who have the same depression diagnosis, and the lack of a connection between symptoms and treatments is a main reason that about half of all people with depression fail to respond to medication or other therapies, and that side effects of these medications are common

However, regular injections are recommended for ongoing benefits

Include leptin-deficient cohorts if mechanistic generalizability is a goal

When stored correctly at 2C-8C, and shielded from light and moisture, the compound maintains its efficacy for up to 24 months, ensuring reliable results in controlled research settings

10.1038/s41584-024-01143-3 10 BlancoF