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Description
This condition comprises a diverse spectrum of hereditary ocular disorders, encompassing around 90 identified genes with thousands of mutations nestled within them

Consequently, sensory receptors (e.g., Polycystins) and downstream effectors (e.g., GLI3 in the Hedgehog pathway) fail to localize properly within the cilium [60] (Fig

Each sample was analyzed in triplicate with ten acquisitions per run using a DelsaMax PRO instrument (Beckman Coulter, USA)

This facilitates local drug enrichment, thereby enhancing therapeutic efficacy while minimizing off-target side effects
10.3389/fimmu.2020.01229 Front Immunol
