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LC-MS/MS was carried out on 500 ng of injected material similar as to aforementioned Proteomics LC-MS analysis with following adaptations: the timsTOF HT mass spectrometer (Bruker Daltonics) was operated in positive mode with enabled trapped Ion Mobility Spectrometry (TIMS) at 100% duty cycle (100 ms ramp and accumulation time)

This review explores how circadian and aging processes interact in mice, humans and long-lived species, aiming to uncover mechanisms of chrono-aging and their implications for healthy longevity

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Lipodystrophy refers to a medical condition characterized by abnormal or degenerative conditions of the body's fat tissue