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Description
In men, chronic insulin resistance reduces testosterone and sperm quality

Early detection and treatment are crucial, as neurological damage from prolonged B12 deficiency may become irreversible if left untreated

Verdict: Limited evidence there are plausible gut-related mechanisms and some encouraging animal findings, but published human outcome data is too sparse and too poorly reported to confirm real clinical benefits [6][1113]
Age-Dependent Decline of NAD+ -Universal Truth or Confounded Consensus

Common sites include the abdomen or thighs
