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This is largely because peptides are too big to be properly absorbed through the intestine walls after oral ingestion
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doi:10.1177/2325967120915704 2282 24 Elizondo-Rodrguez J, Simental-Menda M, Pea-Martnez V, Vilchez-Cavazos F, Tamez-Mata Y, Acosta-Olivo C
Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself
