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The GLP-1 receptor activation partially bypasses leptin pathways, maintaining appetite suppression even as leptin drops

Overall, given the limited number of studies assessing age-related changes in brain GSH levels, we recommend additional investigations (a) for all age groups, but in particular, the understudied middle-aged group, and (b) MRS at UHF (i.e., 7T)
Constant follow-up and lifelong mineral and multivitamin supplementation are recommended [5,53,133]

10.1111/j.1750-3841.2006.00258.x 36 Ghazizadeh-HashemiF.BagheriS.Ashraf-GanjoueiA.MoradiK.ShahmansouriN.MehrpooyaM.et al (2021)
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