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Studies have shown that certain types of B12 including methylcobalamin, adenosylcobalamin, and hydroxycobalamin (6) are preferred over the more common and synthetic form of B12 known as cyanocobalamin

Opening Statement by Roy Pitkin on Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

Hence the skin looks a bit brighter

Some guidelines: Let your blood labs guide your B vitamin intake

In practice, that often means: Your provider may be comfortable starting a standard daily vitamin D supplement without ordering labs first if: You are generally healthy You are taking a modest daily dose in the typical range You do not have bone disease or other conditions that raise concern Your provider is more likely to want vitamin D blood work if: You have a history of osteoporosis or frequent fractures You have conditions that affect vitamin absorption You are on medicines that change vitamin D or calcium metabolism You are considering higher dose or long term vitamin D plans beyond typical daily intake Vitamin B12 Vitamin B12 is crucial for red blood cell formation, nerve health and DNA production