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Terrault, M.D

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Melatonin acts as a free-radical scavenger, regulating free radical generation in the mitochondria.[ref] Cell studies show that melatonin stops mitochondrial fission while enhancing mitophagy (clearance of damaged mitochondria) in liver cells.[ref] In brain cells, melatonin supplementation reduces cell death and restores mitochondrial function through the regulation of autophagy.[ref] When challenged with viral-induced liver failure, melatonin modulates mitophagy, preserving mitochondrial function when needed.[ref][ref] Additional clinical trials of supplemental melatonin: Atopic dermatitis: A clinical trial in kids with atopic dermatitis (eczema) found that 3mg of melatonin per night reduced the rash significantly

Validation of a strategy for HCV antibody testing with two enzyme immunoassays in a routine clinical laboratory

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