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The transport system consists of three main proteins, the first of which is the enzyme carnitine palmitoyltransferase I (CPTI) present in the mitochondrial outer membrane that complexes with a long-chain acyl-CoA synthetase and the voltage-dependent anion channel, while the second transport component is carnitine:acylcarnitine translocase (CACT), an integral inner membrane protein, which complexes with carnitine palmitoyltransferase II (CPTII) located on the matrix side of the inner membrane

High grade glioblastoma is associated with aberrant expression of ZFP57, a protein involved in gene imprinting, and of CPT1A and CPT1C that regulate fatty acid metabolism

42 These regulatory activities within the nervous system are likely to explain the anti-nociceptive properties of ALC

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