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Of note, anaphylaxis, refractory intracranial hypertension, or status epilepticus, reported in cases of NAC overdoses related to prescribing errors [53], attributable to probenecid and NAC treatment was not observed

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Similar immune defects are observed in alcohol-related cirrhosis, including depletion and functional impairment of MAIT (mucosal-associated invariant T) cells and elevated soluble immune checkpoint molecules, such as sTIM-3 ( In our study, we utilized fumarylacetoacetate hydrolase (Fah)-/-, Rag2-/-, common cytokine receptor gamma chain knock-out (FRG-KO) humanized mice engrafted with HLA-A2-positive hepatocytes