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Neelakantan et al

Most patients spend the time reading, working on a laptop, watching a film, listening to music, or simply sleeping

These biofilms can play an important role in infections as they protect pathogenic bacteria from antibacterial substances

The observed bioenergetic disruptions align with mechanisms implicated in diabetic bone disease, supporting the relevance of this model in studying tissue-level responses that may also occur in vivo (Arajo et al
Other studies have shown issues with the ability of the enzyme dopamine beta hydroxylase which catalyzes dopamine into norepinephrine and the norepinephrine transporter enzyme which is involved in the reuptake of norepinphrine into the synaptic terminals (13, 14)
