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Dysesthesia, an abnormal sensation often described as tingling, burning, or numbness in the skin, appeared in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose, compared to just 0.7% on placebo

Management typically includes increasing intake of B12-rich foods, using high-quality B12 supplements, and in some cases receiving B12 injections prescribed by a healthcare provider
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