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2016 Mar;10(1):110

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The cholesterol biosynthetic pathway takes place in the cytosol and is initiated by the enzyme HMG-CoA reductase, the target of statin drugs (see Box 3), to generate the six-carbon molecule mevalonate from one molecule of acetyl-CoA and one molecule of acetoacetyl-CoA (Fig

Furthermore, the addition of a combination of AOXs (ALC, NAC and -lipoic acid) to the cryoprotectant medium of mice embryos resulted in increased blastocyst cryo-survival and viability post-vitrification (216)