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as evident by looking at the molecules, the oxidized form of glutathione is actually two reduced glutathione atoms bound together at the sulfur atoms (1)

152 Dysregulation of Wnt/-catenin signalling is often caused by mutations of various components in the pathway, particularly mutations or silencing of the Wnt tumour suppressor, which occurs frequently in various cancer types, such as adenomatous polyposis coli (APC) mutations, 193 Axin1/2 mutations, 194,195 GSK3 deletions, 196 inactivation mutations of E3 ubiquitin ligase RNF43, 196 and Znrf3

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N-Methyl-D-aspartate receptor-mediated mitochondrial Ca2+ overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca2+ influx