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Anesth Prog 38 [PMC free article] [PubMed] 49.Berlin R, Berlin H, Brante G, Pilbrant (1978) Vitamin B12 body stores during oral and parenteral treatment of pernicious anaemia

Studies have shown that through direct ionization or indirect effects mediated by reactive oxygen species (ROS), IR causes DNA damage, protein modification, and lipid peroxidation in LECs, leading to cell apoptosis or necrosis and lens opacity ( In recent years, ferroptosis, as a new form of cell death, has gained widespread attention for its role in various diseases such as neurodegenerative disorders, ischemiareperfusion injury, and cancer ( Although the crucial role of ferroptosis in various diseases has been widely recognized, its role in ionizing radiation-induced lens damage remains unclear
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Environmental Pollutants: Exposure to heavy metals, cigarette smoke, and chronic pollution increases the demand for glutathione-driven detoxification

More than a century has elapsed since AD was first described in 1906, 64 and significant progress has been made in understanding its pathogenesis, improving diagnosis, and enhancing treatment
