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Keywords: Nucleic acid therapeutics, Nucleic acid drugs, Delivery systems, Nucleic acid delivery challenges, Lipid nanoparticle carriers Graphical abstract 1

It has been shown that serum levels of albumin were significantly reduced and aspartate aminotransferase (AST), alanine aminotransferase (ALT), and total bilirubin levels were significantly increased in cisplatin-treated individuals

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doi: 10.1016/J.TINS.2017.10.006

Thus, LAB are a major component of gut microbiota that play an important role in maintaining the balance of the total microbial community