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4 Chronic stress affects HPA axis activity and cortisol regulation The HPA axis is a key neuroendocrine system that regulates stress responses and represents one of the core pathways mediating stress reactions (Parker et al., 2001

DOI:10.1093/jcag/gwae025 6

SIRT1 plays a crucial role in regulating cellular stress responses and maintaining genomic stability, thereby protecting cells from the detrimental effects of Hcy

[PubMed: 8530602] 35

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