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CYP2E1-mediated increased oxidative stress in hepatocytes upon ALC exposure is expected to induce mir200s, which are packaged in exosomes, secreted, and circulated in the plasma 54

Meanwhile, NETs may promote t-PA resistance in acute ischemic stroke by activating platelets and endothelial cells

In vitro studies of IMC M113V RES described here were performed to complement data from preclinical experiments supporting regulatory submissions, all of which were performed using IMC-M113V

As already discussed above, mitochondria contain enzymes for ATP production, apoptotic signaling, ROS formation, and other processes (Santos et al