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Conclusion In conclusion, the study demonstrated that the addition of l-carnitine enhanced the therapeutic effects of metformin, improving glucose control, reducing depressive behaviors, and ameliorating lipid peroxidation

A randomized study published in 2015 showed for the first time that oral reduced glutathione (GSH) supplementation is effective in raising intracellular glutathione levels (250-1000 mg/day)

However, a trend in favor of omega3 PUFAs supplementation was observed in GSSG levels and glutathione reductase activity at 12 months of intervention between the study groups [28]

doi: 10.1186/s13578-021-00731-0

It promotes glucose uptake into muscle and adipose tissue and suppresses hepatic glucose production, which can cause blood glucose to drop to dangerous levels particularly in fasted states or with inadequate carbohydrate intake