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Unlike many other vitamins, B12 is stored in the liver in substantial quantities, meaning deficiency typically develops gradually over months to years as these reserves become depleted

[Google Scholar] 67.Kalant H Pharmacokinetics of ethanol: Absorption, distribution, and elimination

For most individuals this is dinner, making late-afternoon dosing (4-6pm) ideal

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(3) Health professionals recommend a full blood count and reticulocyte count 7-10 days after starting treatment, and eight weeks to confirm normal blood levels