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However, RavD from the genus Legionella has a papain-like fold and specificity towards linear Ub chains, while no eukaryotic counterpart was reported to cleave Met1-linked Ub chains 22,23

FGF21-sirtuin 3 axis confers the protective effects of exercise against diabetic cardiomyopathy by governing mitochondrial integrity

In previous literature, paclitaxel along with IFN was shown to induce killing of L

(5) In cases of organophosphate or nerve agent poisoning, ipratropium may be used alongside parenteral atropine to alleviate bronchospasm as part of adjunctive management of cholinergic crisis

Conducting high-quality, multicenter RCTs with standardized protocols and extended follow-up will be essential to validate efficacy, clarify mechanisms, and promote wider, evidence-based integration of TCM into comprehensive tinnitus management strategies
