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Description
A cell that is activating MOTS-c-mediated metabolic improvement but is depleted of NAD+ is like an engine receiving a better fuel signal but running low on fuel itself
Biochemistry and molecular biology
However, if oxygen is present, the toxic radical species are reoxidized to their (4) prodrug form, diminishing the bactericidal effects 12,21,22,23
2016;6(7):e447e447
425 Peptide targeting of subcellular organelles offers a promising strategy to guide NADs to dysfunctional organelles, thus achieving optimal therapeutic effects
