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At 6 months post-vaccination, BNSP333-OspA-HVG vaccinated mice had about 50-fold more anti-OspA antibodies than Vanguard vaccinated mice (Fig

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[DOI] [PubMed] [Google Scholar] 22.Lenzi A, Sgr P, Salacone P, Paoli D, Gilio B, Lombardo F, et al

For this reason, an overdose is very rare and it's generally considered safe, even at high doses

Interesting data has come forth on the internalization pattern of 1B -ARs