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Furthermore, FXR transcriptionally activates Acsl4 in intestinal epithelial cells (IECs), promoting ferroptosis and subsequently impairing ILC3 function, and can induce Wnt2b in cancer-associated fibroblasts (CAFs) within the tumor stroma, fostering a pro-tumorigenic niche (92, 93)
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Int J Mol Sci 23:15116
doi: 10.3390/biomedicines10071593
Discussion This is the first LC-MS/MS-based metabolic profiling report from Bangladesh analyzing carnitine-acylcarnitine metabolites in the blood of congenital hypothyroid patients receiving thyroid hormone replacement therapy
