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While it is generally considered safe when used as directed, many people are unaware of how this common compound interacts with the bodys internal chemistry

In a 2001 study published in Endocrinology , Heffernan and colleagues reported that chronic AOD-9604 administration reduced body weight gain, decreased adipose tissue mass, and increased fat oxidation in obese mice without altering IGF-1 levels or glucose metabolism effects that were abolished in beta3 adrenergic receptor (3-AR) knockout mice, implicating 3-AR signaling as the mechanism of action [1]

Studies indicate that cells will make a glycolytic switch when NAD + demand is high and exceeds ATP demand, therefore skewing the NAD + use for this pathway 341

Fun fact: It was first discovered in 1907 and naturally occurs in the production of sake, soy sauce, and miso

Imagine waking up and actually feeling the difference