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On the one hand, ROS induce oxidative damage to cysteine residues within the MutS complex (MSH2-MSH6 heterodimer), specifically impairing its ATPase-dependent DNA mismatch recognition capacity

The iodine is turning from orange to black
pneumoniae is traditionally considered a typical extracellular pathogen

Tracking burden also increases with longer cycles, needing more frequent assessments and possibly increasing research costs and subject burden
