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These include inflammatory and autoimmune diseases such as rheumatoid arthritis, atherosclerosis, and inflammatory bowel disease, fibrotic disorders like hepatic, pulmonary, muscle and adipose tissue fibrosis, cancer particularly through TAMs which mediate immunosuppression and facilitate tumor progression and metastasis, metabolic diseases including obesity-associated adipose tissue inflammation, diabetes and its complications, and neurodegenerative conditions such as Alzheimers disease, Parkinsons disease, multiple sclerosis, and stroke, as well as infection ( Figure 4 )

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2019 [4] V

3a), we quantified mtDNA mutation loads in sorted tumor-infiltrating immune populations

Hu and co-workers also showed that the brain targeting efficiency was impacted by the types of phospholipids used in the preparation of liposomes [47]