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*Correspondence: Jan Born [email protected] This article was submitted to Clinical Diabetes, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Many preclinical studies have shown that solely targeting key metabolic enzymes or their associated signaling pathways often fails to achieve satisfactory antitumor outcomes