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Immunohistochemical studies show that labeling for OCTN 1, 2 and 3 is distributed in many regions of mouse brain and spinal cord in a pattern consistent with possible roles in modulating bioenergetics and cholinergic neurotransmission [51]

10.1002/jcp.25049 10 CastiglioneF.HedlundP.Van der AaF.BivalacquaT

This group had previously shown in the streptozotocin (STZ)-induced uncontrolled diabetic rat that intracerebroventricular administration of leptin returned glucose to normal, restored BAT glucose uptake, and normalized serum T 4 and BAT UCP1 mRNA levels (92)

Methods and Materials 1

Jansen R, Milaneschi Y, Schranner D, Kastenmuller G, Arnold M, Han X, et al