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Figure 10 illustrates the biosynthetic pathway of carotenoids from FPP in the leaves of higher plants, highlighting the enzyme-catalyzed reactions involved

Both Nrf1 and Nrf2 overexpression induced the human GS promoter activity [144]

When considering the interaction between loss of pink-1 and metabolite addition, these mutant lines confirm RNAi results, suggesting epistatic regulation of metabolite activity by loss of pink-1 (Figures 4d and e) but not pdr-1, which appears to acts in parallel to metabolite toxicity

Several viral infections, and the progression of virus-induced diseases, especially those associated with COVID-19, are characterized by an alteration in the intracellular redox balance (144, 145) and respiratory diseases, known risk factors for developing severe illness and death in patients with SARS-CoV-2 and COVID-19 disease

163 As an example, Tiriveedhi et al reported that lung transplant patients, who developed chronic lung allograft rejection, show increased defensin and decreased serum AAT levels along with high concentrations of AAT-defensin complexes in their bronchial lavage