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[Abstract]2025 Mar 15:991:177311

pmid:11149440 5

The active HGF consists of 697 or 692 amino acids as a heterodimeric composed of -chain and -chain (Kirchhofer et al., 2004)

Unlike BVZ and Aflibercept, tyrosine kinase inhibitors, which are small molecules able to interact with the kinase domain on the VEGFRs, showed a remarkable clinical benefit when used as single agents, and with no added value when combined with chemotherapy
