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Because it is a small fragment of a naturally occurring hormone (-MSH), risk appears lower but human clinical safety data remain limited

10.1016/j.jddst.2022.104087

In addition, it is exceptionally active as both an aminotransferase and a -lyase with many selenocysteine Se -conjugates

When used as a date-rape drug, GHB may be mixed with alcoholic beverages, producing a combination that is dangerous and deadly

Despite these benefits, some PPAR agonists, such as rosiglitazone and pioglitazone, have been associated with increased heart failure due to direct or indirect cardiac effects, such as fluid retention (3)
