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Consistent with expectations, bona fide p53 targets including HDM2 and CDKN1A were among the most highly up-regulated genes in Control cells, whereas genes known to be negatively regulated by p53, such as E2F2 , were strongly down-regulated (el-Deiry et al, 1993

Four-week ketogenic diet intervention increased the transcription and histone acetylation of Grin2a and Grin2b in Shank3-deficient rats and ameliorate the decreased NMDAR synaptic function in PFC neurons

Protein reactivity of 3,4-dihydroxyphenylacetaldehyde, a toxic dopamine metabolite, is dependent on both the aldehyde and the catechol

Swisher SG , Mansfield P

A., Karaca, F., Beer, S