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ZG: Conceptualization, Writing review & editing

One may trigger a signal, but they are not the same object
Gln24, Cys169, Leu170, Asp171, Ala172 and Ala185 have resulted in conversion of loop to helix due to replacement of isoleucine to valine at position 105

Levonen A.-L
10.3389/FIMMU.2019.02546/PDF [DOI] [PMC free article] [PubMed] [Google Scholar] Yang Y, Wang X, Xiao A et al (2022) Ketogenic diet prevents chronic sleep deprivation-induced Alzheimers disease by inhibiting iron dyshomeostasis and promoting repair via Sirt1/Nrf2 pathway
