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Similarly, some studies have also found that in skeletal muscle of an ALS mouse model, increased Nrf2 levels occur at very early time points, even before the onset of movement impairments (Kraft et al
This is supported by the very rare occurrence of mutations in IGF-axis genes in common cancers, implying that the IGF axis is seldom the primary driver of tumorigenesis [51, 52]

doi: 10.3390/md17010039

Int J Mol Sci 17(1):14 Darr U, Sussman NL (2020) Drug-Induced Liver Injury in the Setting of Analgesic Use

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