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In those, loss of NRF2 resulted in a more rapid onset and more severe clinical course of the EAE model, which was accompanied by increased glial activation, exacerbated spinal cord damage, and axonal degeneration as well as increased levels of proinflammatory cytokines (Johnson et al., 2010

In conclusion, we demonstrated an effective strategy to employ protein-reactive platinum functionalities to generate drug conjugates, which augment traditional cytotoxic chemotherapeutic agents

Thus, we believe that our current observations are the beginning of a complex and rich connection between tumor metabolism and tumor biology

van der Pols JC, Xu C, Boyle GM, Hughes MC, Carr SJ, Parsons PG, et al

BPC 157 Therapy and the Permanent Occlusion of the Superior Sagittal Sinus in Rat: Vascular Recruitment
