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At the same time, CAR-T cells capable of expressing receptors for specific chemokines present in the tumor microenvironment are under development

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Ice crystal formation physically disrupts the molecular structure of both the water and benzyl alcohol, rendering the preservative ineffective and compromising sterility

The mechanism is not entirely clear, but likely includes increased nucleotide and glutathione synthesis [49, 103]

One study suggests a cutoff value of 11.7 mm for the pretibial region as a diagnosis of lipedema (79% sensitivity, 96% specificity), followed by 17.9 mm for the thigh (67% sensitivity, 94% specificity) and 8.4 mm for lateral leg thickness (78% sensitivity, 84% specificity) 75