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Funding The work was supported by a grant financed by the National Science Centre in Poland over the course of the realization of the project: "Exploring the role and therapeutic potential of sex hormone binding globulin (SHBG) in the course of insulin resistance, inflammation, lipotoxicity in adipose stem progenitor cells and adipocytes in equine metabolic syndrome (EMS) mares (No 2019/35/B/NZ7/03651)

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p = 0.018) and direct BL ( p = 0.008) in PD populations ( Current evidence indicates that BL levels are elevated in PD patients which progressively decline with disease duration and show an inverse correlation with levodopa equivalent daily dose