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Chronic alcohol consumption leads to malnutrition with dysfunctions in protein and lipid metabolism which affect the metabolic pathways and progression of ALN symptoms within the central and peripheral nervous systems [89]

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However, the data on the contemporary prevalence of CKD across different regions required to gather the considerable information for present and future projections are relatively sparse, while it is reported that the kidney registries in different regions of Asia have mostly been restricted to systematic data collection directly to patients with kidney failure requiring kidney replacement therapy [4]