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The main characteristics of Mller cell gliosis are cell hypertrophy, with thickening of both somas and processes, proliferation, as well as increased expression of cytoskeleton constituent proteins such as vimentin or GFAP, and decreased expression of GS ( During gliosis, Mller cells will also contribute to the formation of glial scars, which can inhibit the remodeling and normal regeneration of damaged retinal tissue (Lu et al., 2011

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[DOI] [PubMed] [Google Scholar] 99.Lyvers M

studied five copper complexes with bis-Schiff base ligands, of which complexes 1-3 are mononuclear and 4-5 are dinuclear([Cu (L 1)] (1), [Cu (L 2)] (2), [Cu (L 3)] (3), [Cu 2 (L 4) (OAc)] (4), and [Cu 2 (L 5) (HCOO)] (5) bearing the bis-Schiff base ligands of bis (5-chlorosalicylidene) -1,3-propanediamine (H 2 L 1), bis (5-chlorosalicylidene) -2-methyl-1,3-propanediamine (H 2 L 2), bis (5-bromosalicylidene) -2-methyl-1,3-propanediamine (H 2 L 3), bis (5-chlorosalicylidene) -2-hydroxyl-1,3-propanediamine (H 3 L 4), and bis (5-bromosalicylidene) -2-hydroxyl-1,3-propanediamine (H 3 L 5), respectively)

Across the various plant species, the expression of WRKY genes plays a pivotal role in response to these conditions, helping plants to adapt [362,363]