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Lancet 2012;379:2373-82

1,50,51,52 Insulin resistance, even without overt hyperglycemia, independently increases DN risk by causing peripheral nerve damage

For example, because during exercise oxygen consumption can increase by a factor of more than 10, taking high doses of antioxidants might interfere with proper exercise recovery

doi: 10.3389/fimmu.2020.626295

Indexes of the severity of liver disease are: Serum bilirubin, which represents secretory function Prothrombin time or international normalized ratio, which reflects synthetic ability Thrombocytopenia can result from the direct toxic effects of alcohol on bone marrow or from splenomegaly, which accompanies portal hypertension